Cancer through the Lens of Evolution and Ecology (Original PDF from Publisher)
- Format: Publisher PDF
- Posted Date: 25 Feb 2025
- Posted By: AfkEbooks
Specification
| Published Year | 2024 |
|---|---|
| Language | English |
| Publisher | CRC Press |
| Edition : | 1 |
| Format : | Publisher PDF |
| File Size : | 20.4 |
| ISBN : | 978-1032310770, 9781040027684, 9781032310787, 9781003307921, 9781040027660 |
Description
By Jason A. Somarelli, Norman A. Johnson
Cancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.
Key Features
- Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated.
- Offers insights from leading scholars in cancer biology, ecology and evolutionary biology.
- Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment.
- Integrates basic and applied sciences of oncology and evolutionary biology.
Product Details
- Publisher : CRC Press; 1st edition (July 5, 2024)
- Language : English
- Paperback : 214 pages
- ISBN-10 : 1032310774
- ISBN-13 : 978-1032310770