This course will provide a comprehensive review and update of the pathologic diagnosis and clinical significance of benign, in situ and malignant lesions of the breast identified in surgical specimens and core needle biopsies. The most current adjunctive immunohistochemical and molecular studies to assist in the diagnosis and classification of benign and malignant breast lesions and to guide patient management will be emphasized. This course includes a combination of lectures, interactive microscopy sessions, and a panel Q&A.

Upon completion of this educational activity, learners will be able to:

• Describe the diagnostic criteria and clinical significance of a variety of benign, in situ and malignant breast lesions encountered in surgical specimens and core needle biopsies
• Discuss differential diagnostic problems in breast pathology and the uses and limitations of ancillary immunohistochemical and molecular tests in arriving at the correct diagnosis
• Discuss prognostic and predictive assays in patients with breast cancer

Learning Objectives: After participating in this educational initiative, attendees will achieve the following learning objectives:

1. In-depth Understanding: Articulate the diagnostic criteria and clinical significance associated with a diverse array of benign, in situ, and malignant breast lesions frequently encountered in surgical specimens and core needle biopsies.
2. Differential Diagnosis Proficiency: Engage in discussions regarding diagnostic challenges commonly encountered in breast pathology. Comprehend the utility and constraints of supplementary immunohistochemical and molecular assays in facilitating precise diagnoses.
3. Insights into Patient Management: Delve into the realm of prognostic and predictive assays applicable to patients afflicted with breast cancer. Gain proficiency in interpreting these assays, which play a crucial role in guiding treatment decisions.

This educational course is an indispensable platform for clinicians, pathologists, and researchers seeking to augment their grasp of contemporary issues in breast pathology. By integrating cutting-edge knowledge and practical methodologies, participants will be well-equipped to address diagnostic uncertainties and contribute to optimal patient care.

TOPICS

- Lobular, Mucinous, and Fibroepithelial Lesions – Laura C. Collins, MD

- Lumpectomy Margin Evaluation, Lesions, and Salivary Gland-like Tumors of the Breast – Stuart J. Schnitt, MD

- Papillary Lesions, Spindle Cell Lesions, and Uncommon Breast Cancers – Kimberly H. Allison, MD

- Neoadjuvant Chemotherapy, Vascular Lesions, and Intraductal Proliferative Lesions – Gregory R. Bean, MD, PhD

- Ductal, Nipple, Inflammatory, and Reactive Lesions – Edi Brogi, MD, PhD

- Small Glandular Proliferations, Fibroepithelial Lesions, and ER, PR, and HER2 Testing – Ashley M. Cimino-Mathews, MD

- Hot and Controversial Topics in Breast Pathology

- Q&A Panel Discussions

Original release date: July 8, 2023