by Jean-Francois Dufour

Signalling Pathways in Liver Diseases 3E again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signalling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format.

With increased focus on the comprehension of cellular mechanisms involved in steatohatitis, cirrhosis and liver tumours, which has led in changes to the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as:

• Autophagy
• Notch Pathway
• PI3K/PTEN Signaling in Liver Diseases
• Sirtuins
• Hepcidin and Iron
• Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis
• Oxidative Stress and Signaling in the Liver

Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom will provide write a clear yet comprehensive review of their chosen topic. Chapters will contain clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge.

Signalling Pathways in Liver Diseases 3E is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

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