A Practical Guide to Designing Phase II Trials in Oncology - Afkebooks - Medical ebooks for Doctors

A Practical Guide to Designing Phase II Trials in Oncology

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published date: 05 Jul 14

by Sarah R. Brown, Walter M. Gregory, Christopher J. Twelves, Marc E. Buyse, Mahesh K. Parmar

A comprehensive and practical overview of the identification, conduct and analysis of optimal Phase II trial design.

Choosing Your Phase II Trial Design demonstrates how to approach trial design when there are various options available, such as multiple possible outcome measures, and to use the key characteristics provided to make an informed decision regarding which specific trial design to choose. It sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization. Real life examples and case studies featured throughout the book are accompanied by illustrations using a flow diagram, highlighting the choices made for each key point throughout the process.

Choosing Your Phase II Trial Design provides an introduction to key concepts for beginners and explores lesser known and alternative approaches to trial design for the more experienced researcher.

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