by Tasuku Honjo (Editor), Michael Reth (Editor), Andreas Radbruch (Editor), Frederick Alt (Editor)

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production.All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes.

Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.

• Covers signaling mechanisms regulating B cell differentiation
• Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab
• Contains studies on B cell tumors from various stages of B lymphocytes
• Offers an integrated view of all aspects of B cells to produce a normal immune response

Audience: Research level immunologists, molecular biologists and geneticists.

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