Thisbook provides a thorough introduction to the topic of mathematical modeling ofelectrical activity in the heart, from molecular details of ionic channeldynamics to clinically derived patient-specific models. It discusses howcellular ionic models are formulated, introduces commonly used models andexplains why there are so many different models available. The chapters covermodeling of the intracellular calcium handling that underlies cellularcontraction as well as modeling molecular-level details of cardiac ion channels,and specialized topics such as cardiomyocyte energetics andsignalling pathways. It is an excellent resource for experienced andspecialized researchers in the field, but also biological scientists with alimited background in mathematical modelling and computational methods.

Key Features

• Thorough introduction to the topic of mathematical modeling of electrical activity in the heart
• Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations
• In addition to being experts in the field, the contributing authors are expert science communicators